Age at first birth and risk of urinary incontinence after delivery: a dose–response meta-analysis

Studies investigating the impact of age at first birth on urinary incontinence after delivery have reached inconsistent conclusions. We performed this systematic review and meta-analysis of studies assessing the risk of urinary incontinence after delivery, regardless of the type, with age at first b...

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Veröffentlicht in:Scientific reports 2022-10, Vol.12 (1), p.16588-16588, Article 16588
Hauptverfasser: Ren, Yongcheng, Hu, Qing, Zou, Haiyin, Xue, Meifang, Tian, Xinjie, Cao, Fuqun, Yang, Lei
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Sprache:eng
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Zusammenfassung:Studies investigating the impact of age at first birth on urinary incontinence after delivery have reached inconsistent conclusions. We performed this systematic review and meta-analysis of studies assessing the risk of urinary incontinence after delivery, regardless of the type, with age at first birth. MEDLINE via PubMed and Web of science databases were searched up to March 13, 2021. Restricted cubic splines were used to model the dose–response association. Twelve publications were included in this meta-analysis. The summary odds ratio (OR) and 95% confidence interval (CI) per 1-year increase in age at first birth were 1.01 (95% CI (0.99, 1.02)) for urinary incontinence (America: 1.00 (0.99, 1.00); Europe: 1.03 (1.00, 1.06); Asian: 0.99 (0.89, 1.10)). A non-linear dose–response ( P nonlinearity  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-022-19809-x