Epileptic activity in a patient with serum anti-GAD antibody-positive limbic encephalitis
Limbic encephalopathy (LE) is an entity, which may present with memory loss, seizure, psychiatric symptoms and is usually accompanied by neuro-radiology imaging findings. In recent years, antibody tests that can be studied in detail have gained importance as markers. Glutamic acid decarboxylase anti...
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Veröffentlicht in: | Archives of Epilepsy 2020-04, Vol.26 (1), p.45-48 |
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Sprache: | eng |
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Zusammenfassung: | Limbic encephalopathy (LE) is an entity, which may present with memory loss, seizure, psychiatric symptoms and is usually accompanied by neuro-radiology imaging findings. In recent years, antibody tests that can be studied in detail have gained importance as markers. Glutamic acid decarboxylase antibody (GAD-Ab) has been reported to be mainly responsible for non-paraneoplastic syndromes. GAD-Ab positivity is predominantly seen in young adult females and temporal lobe epilepsy. Patients with GAD-Ab positive have been reported to respond well or partial to immunotherapy. In this article, we report a 38-year-old woman presenting with seizure and diagnosed with limbic encephalitis who had magnetic resonance imaging and electroencephalograhy findings accompanied by serum GAD-ab positivity was reported. GADAb is considered to play an important role in the prognosis of LE and the other neurological syndromes and should be investigated further. |
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ISSN: | 1300-7157 2792-0550 |
DOI: | 10.14744/epilepsi.2019.16870 |