P16-09. Adenovirus 5 vector HIV vaccination does not affect mucosal homing markers on Ad5-specific CD4+ T-cells in humans

Conclusion This data suggests that vaccination does not induce a differential measurable effect on mucosal trafficking in circulating Ad-specific CD4+ T cells between the serogroups and therefore contradicts a role for Ad-specific T-cells in the possible increased risk of HIV infection observed duri...

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Veröffentlicht in:Retrovirology 2009-10, Vol.6 (S3), p.P238-P238, Article P238
Hauptverfasser: Hutnick, N, Carnathan, D, Dubey, S, Cox, K, Ratcliffe, S, Robertson, MN, Casimiro, DR, Ertl, HC, Betts, MR
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Sprache:eng
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Zusammenfassung:Conclusion This data suggests that vaccination does not induce a differential measurable effect on mucosal trafficking in circulating Ad-specific CD4+ T cells between the serogroups and therefore contradicts a role for Ad-specific T-cells in the possible increased risk of HIV infection observed during the STEP trial.
ISSN:1742-4690
1742-4690
DOI:10.1186/1742-4690-6-S3-P238