Assessment of endothelial function by brachial artery flow mediated dilatation in microvascular disease

Cardiac syndrome X is an important therapeutic and diagnostic challenge to physician. Study of Csx patients may help to understand the pathophysiology of coronary microcirculation and to gain an insight on the management of these group patients. We measured the flow mediated dilation of the brachial artery both endothelium dependent and independent vasodilatation by high resolution ultrasound in 30 cardiac syndrome X patients and matched with 30 healthy control subjects. Significantly decreased flow mediated dilatation was observed in patients when compared to control (9.42±7.20 vs 21.11±9.16 p