The Challenges and Opportunities in the Development of MicroRNA Therapeutics: A Multidisciplinary Viewpoint

The Challenges and Opportunities in the Development of MicroRNA Therapeutics: A Multidisciplinary Viewpoint

microRNAs (miRs) are emerging as attractive therapeutic targets because of their small size, specific targetability, and critical role in disease pathogenesis. However,

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Bibliographische Detailangaben
Veröffentlicht in:Cells (Basel, Switzerland) Switzerland), 2021-11, Vol.10 (11), p.3097
Hauptverfasser: Momin, Mohammad Yahya, Gaddam, Ravinder Reddy, Kravitz, Madeline, Gupta, Anisha, Vikram, Ajit
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biosynthesis
Clinical trials
Complementarity
Drug development
Enzymes
Exosomes - metabolism
Gene expression
Gene Transfer Techniques
Humans
Liposomes - chemistry
MicroRNAs - administration & dosage
MicroRNAs - blood
MicroRNAs - therapeutic use
miR delivery
miRNA
Models, Biological
Nanoparticles - chemistry
peptide nucleic acids
plant-derived miRs
Proteins
Review
RNA polymerase
Stem cells
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Beschreibung
Zusammenfassung:microRNAs (miRs) are emerging as attractive therapeutic targets because of their small size, specific targetability, and critical role in disease pathogenesis. However,
ISSN:2073-4409
2073-4409
DOI:10.3390/cells10113097