Bimatoprost Effects on Aqueous Humor Dynamics in Monkeys

The effects of bimatoprost on aqueous humor dynamics were quantified in monkey eyes. Uveoscleral outflow was measured by the anterior chamber perfusion method, using FITC-dextran. Total outflow facility was determined by the two-level constant pressure method. Aqueous flow was measured with a scanni...

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Veröffentlicht in:Journal of Ophthalmology 2010-01, Vol.2010 (2010), p.1-5
Hauptverfasser: Woodward, David F., Krauss, Achim H.-P., Nilsson, Siv F. E.
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Sprache:eng
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Zusammenfassung:The effects of bimatoprost on aqueous humor dynamics were quantified in monkey eyes. Uveoscleral outflow was measured by the anterior chamber perfusion method, using FITC-dextran. Total outflow facility was determined by the two-level constant pressure method. Aqueous flow was measured with a scanning ocular fluorophotometer. Uveoscleral outflow was 0.96±0.19 μL min−1 in vehicle-treated eyes and 1.37±0.27 μL min−1 (n=6; P
ISSN:2090-004X
2090-0058
2090-0058
DOI:10.1155/2010/926192