Systemic inflammatory syndrome in children during COVID-19 pandemic in Ceará state, northeastern Brazil: an observational study

In this study, we report the occurrence of multisystemic inflammatory syndrome among 64 children (2 deaths) with recent severe acute respiratory syndrome-related coronavirus 2 (SARS-COV-2) infections in the northeast region of Brazil. The major clinical symptoms and signs reported were exanthema (60...

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Veröffentlicht in:Revista da Sociedade Brasileira de Medicina Tropical 2021-01, Vol.54, p.e0383-e0383
Hauptverfasser: Farias, Luís Arthur Brasil Gadelha, Almeida, Magda Moura de, Linhares, Pâmela Maria Costa, Brito Alves, Bruno Cavalcante Fales de, Duarte Filho, Roberto Jorge Colares, Leite, Roberio Dias, Safadi, Marco Aurelio Palazzi, Cavalcanti, Luciano Pamplona de Góes
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Sprache:eng
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Zusammenfassung:In this study, we report the occurrence of multisystemic inflammatory syndrome among 64 children (2 deaths) with recent severe acute respiratory syndrome-related coronavirus 2 (SARS-COV-2) infections in the northeast region of Brazil. The major clinical symptoms and signs reported were exanthema (60.9%), abdominal pain (56.3%), nausea and vomiting (46.9%), diarrhea (37.5%), and dyspnea (37.5%). Laboratory findings revealed that the levels of C-reactive protein (75.0%), hemoglobin (51.6%), D-dimer (48.4%), lymphocytes (43.8%), LDH (45.3%), AST (42.2%), ALT (51.6%), and ferritin (48.4%) were above the reference values for a given age and gender. The clinical findings were similar to those observed in Kawasaki disease, although it represents a separate entity, emphasizing the need for proactive surveillance and early treatment.
ISSN:0037-8682
1678-9849
1678-9849
DOI:10.1590/0037-8682-0383-2021