Propensity for seizure-related cortical laminar necrosis in hepatic encephalopathy

Propensity for seizure-related cortical laminar necrosis in hepatic encephalopathy

•Hepatic encephalopathy may predispose to seizure-related cortical laminar necrosis.•Elevated ammonia levels potentially compound the excitotoxic effects of epilepsy.•Early identification and treatment of seizures in liver disease could be protective.

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Bibliographische Detailangaben
Veröffentlicht in:Epilepsy & behavior reports 2019-01, Vol.12, p.100348-100348, Article 100348
Hauptverfasser: Peters, James, Vijiaratnam, Nirosen, Wong, Joseph Z.W., Jitpiriyaroj, Sonia, Chandra, Ronil V., Kempster, Peter A.
Format: Artikel
Sprache:eng
Schlagworte:
Cortical laminar necrosis
Epileptogenic zone
Hepatic encephalopathy
Hyperammonaemia
Status epilepticus
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Beschreibung
Zusammenfassung:•Hepatic encephalopathy may predispose to seizure-related cortical laminar necrosis.•Elevated ammonia levels potentially compound the excitotoxic effects of epilepsy.•Early identification and treatment of seizures in liver disease could be protective.
ISSN:2589-9864
2589-9864
DOI:10.1016/j.ebr.2019.100348