West Nile virus RNA in tissues from donor associated with transmission to organ transplant recipients

We identified West Nile virus (WNV) RNA in skin, fat, muscle, tendon, and bone marrow from a deceased donor associated with WNV transmission through solid organ transplantation. WNV could not be cultured from the RNA-positive tissues. Further studies are needed to determine if WNV can be transmitted...

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Veröffentlicht in:	Emerging infectious diseases 2013-09, Vol.19 (9), p.1518-1520
Hauptverfasser:	Blau, Dianna M, Rabe, Ingrid B, Bhatnagar, Julu, Civen, Rachel, Trivedi, Kavita K, Rollin, Dominique, Hocevar, Susan N, Kuehnert, Matthew, Staples, J Erin, Zaki, Sherif R, Fischer, Marc
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Dispatch Health aspects Humans Male Organ transplant recipients organ transplantation Organ Transplantation - adverse effects Polymerase Chain Reaction RNA RNA, Viral Tissue Donors tissues Transplantation of organs, tissues, etc viruses West Nile fever West Nile Fever - diagnosis West Nile Fever - transmission West Nile virus West Nile virus - genetics WNV
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Beschreibung
Zusammenfassung:	We identified West Nile virus (WNV) RNA in skin, fat, muscle, tendon, and bone marrow from a deceased donor associated with WNV transmission through solid organ transplantation. WNV could not be cultured from the RNA-positive tissues. Further studies are needed to determine if WNV can be transmitted from postmortem tissues.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid1909.130365