Severe acidosis due to 5-oxoprolinase inhibition by flucloxacillin in a patient with shoulder prosthesis joint infection

Severe acidosis due to 5-oxoprolinase inhibition by flucloxacillin in a patient with shoulder prosthesis joint infection

We report a case of a 64-year-old female patient with severe metabolic acidosis. Inhibition of 5-oxoprolinase by flucloxacillin was found to be the cause of the metabolic derailment.

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Veröffentlicht in:Journal of bone and joint infection 2022-04, Vol.7 (2), p.71-74
Hauptverfasser: Lenz, Julia Elisabeth, Alt, Volker, Dienemann, Thomas
Format: Artikel
Sprache:eng
Schlagworte:
Acidosis
Health aspects
Implants, Artificial
Prosthesis
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Beschreibung
Zusammenfassung:We report a case of a 64-year-old female patient with severe metabolic acidosis. Inhibition of 5-oxoprolinase by flucloxacillin was found to be the cause of the metabolic derailment.
ISSN:2206-3552
2206-3552
DOI:10.5194/jbji-7-71-2022