Association of changes of retinal vessels diameter with ocular blood flow in eyes with diabetic retinopathy

We investigated morphological changes of retinal arteries to determine their association with the blood flow and systemic variables in type 2 diabetes patients. The patients included 47 non-diabetic retinopathy eyes, 36 mild or moderate nonproliferative diabetic retinopathy (M-NPDR) eyes, 22 severe...

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Veröffentlicht in:	Scientific reports 2021-02, Vol.11 (1), p.4653-4653, Article 4653
Hauptverfasser:	Ueno, Yoshitaka, Iwase, Takeshi, Goto, Kensuke, Tomita, Ryo, Ra, Eimei, Yamamoto, Kentaro, Terasaki, Hiroko
Format:	Artikel
Sprache:	eng
Schlagworte:	692/308 692/699 Aged Arteries Blood flow Blood pressure Blood vessels Case-Control Studies Cross-Sectional Studies Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - complications Diabetic retinopathy Diabetic Retinopathy - complications Diabetic Retinopathy - pathology Eye Female Humanities and Social Sciences Humans Hypertension Low density lipoprotein Male Middle Aged multidisciplinary Multiple regression analysis Optics Regional Blood Flow Retina Retinal Vessels - pathology Retinopathy Retrospective Studies Science Science (multidisciplinary)
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Zusammenfassung:	We investigated morphological changes of retinal arteries to determine their association with the blood flow and systemic variables in type 2 diabetes patients. The patients included 47 non-diabetic retinopathy eyes, 36 mild or moderate nonproliferative diabetic retinopathy (M-NPDR) eyes, 22 severe NPDR (S-NPDR) eyes, 32 PDR eyes, and 24 normal eyes as controls. The mean wall to lumen ratio (WLR) measured by adaptive optics camera was significantly higher in the PDR groups than in all of the other groups (all P
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-021-84067-2