Fatal Systemic Capillary Leak Syndrome after SARS-CoV-2 Vaccination in Patient with Multiple Myeloma

A young man with smoldering multiple myeloma died of hypotensive shock 2.5 days after severe acute respiratory syndrome coronavirus 2 vaccination. Clinical findings suggested systemic capillary leak syndrome (SCLS); the patient had experienced a previous suspected flare episode. History of SCLS may...

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Veröffentlicht in:	Emerging infectious diseases 2021-11, Vol.27 (11), p.2973-2975
Hauptverfasser:	Choi, Gwang-Jun, Baek, Seon Ha, Kim, Junmo, Kim, Jung Ho, Kwon, Geun-Yong, Kim, Dong Keun, Jung, Yeon Haw, Kim, Sejoong
Format:	Artikel
Sprache:	eng
Schlagworte:	Ad26.COV2.S Autopsies Blood pressure Case studies Causes of Clarkson disease coronavirus disease Coronaviruses COVID-19 COVID-19 diagnostic tests COVID-19 vaccine COVID-19 vaccines Disease control Edema Heart rate Hospitals Hypotension Immunization Influenza Laboratories monoclonal gammopathy Multiple myeloma Pathophysiology Patient outcomes Patients Peritoneal dialysis Severe acute respiratory syndrome coronavirus 2 Vomiting
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Zusammenfassung:	A young man with smoldering multiple myeloma died of hypotensive shock 2.5 days after severe acute respiratory syndrome coronavirus 2 vaccination. Clinical findings suggested systemic capillary leak syndrome (SCLS); the patient had experienced a previous suspected flare episode. History of SCLS may indicate higher risk for SCLS after receiving this vaccine.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2711.211723