Effect of drug resistance on negative conversion of sputum culture in patients with pulmonary tuberculosis

Highlights • Resistance to anti-tuberculosis (anti-TB) drugs lowers culture conversion rates in the early phase of anti-TB treatment. • The effect of the drug resistance pattern on conversion of sputum culture is most evident at 8 weeks. • Resistance to anti-TB drugs prolongs the time to culture con...

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Veröffentlicht in:	International journal of infectious diseases 2016-01, Vol.42 (C), p.64-68
Hauptverfasser:	Kim, Joohae, Kwak, Nakwon, Lee, Ha Youn, Kim, Taek Soo, Kim, Chang-Ki, Han, Sung Koo, Yim, Jae-Joon
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antitubercular Agents - therapeutic use Conversion time Drug resistance Drug Resistance, Multiple, Bacterial Female Humans Infectious Disease Male Middle Aged Pulmonary/Respiratory Sputum - microbiology Tuberculosis Tuberculosis, Pulmonary - drug therapy Tuberculosis, Pulmonary - microbiology
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Beschreibung
Zusammenfassung:	Highlights • Resistance to anti-tuberculosis (anti-TB) drugs lowers culture conversion rates in the early phase of anti-TB treatment. • The effect of the drug resistance pattern on conversion of sputum culture is most evident at 8 weeks. • Resistance to anti-TB drugs prolongs the time to culture conversion.
ISSN:	1201-9712 1878-3511
DOI:	10.1016/j.ijid.2015.11.018