Nonlinear Light Microscopy by a 1.2- $\mu$m Fiber-Laser-Based Femtosecond Dispersive Wave Source

A fiber-laser-based femtosecond dispersive wave laser source, operated within the 1.2to 1.3-μm bio-penetration wavelength window, and its application on nonlinear light microscopy were both demonstrated in this paper. This portable 1.2-μm femtosecond fiber-optic source was composed of an all-fiber 1...

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Veröffentlicht in:IEEE photonics journal 2015-06, Vol.7 (3), p.1-8
Hauptverfasser: Wang, Hsien-Yi, Huang, Shiuan-Wen, Li, Dean-Ru, Lin, Bor-Shyh, Chan, Ming-Che
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Sprache:eng
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Zusammenfassung:A fiber-laser-based femtosecond dispersive wave laser source, operated within the 1.2to 1.3-μm bio-penetration wavelength window, and its application on nonlinear light microscopy were both demonstrated in this paper. This portable 1.2-μm femtosecond fiber-optic source was composed of an all-fiber 1.55-μm mode-locked erbium-doped fiber laser as the excitation source and a nonlinear fiber as a frequency up converter. The 1.2-μm femtosecond radiations with an up to a 55-mW output power and a 125-fs pulsewidth were experimentally demonstrated. By the fiber-based 1.2-μm femtosecond dispersive wave source, nonlinear laser scanning microscopy, including two-photon fluorescence and second-harmonic generation microscopy, was also performed within the 1.2to 1.3-μm bio-penetration window in this report. The fiber-based 1.2-μm femtosecond light source, with a simple system configuration, turn-key operation, and a miniaturized package, shows great potential for nonlinear light microscopy and other related applications outside of the laboratory.
ISSN:1943-0655
1943-0647
DOI:10.1109/JPHOT.2015.2432077