Characteristics of suboptimal immune response after initiating antiretroviral therapy among people living with HIV with a pre-treatment CD4 T cell count <200 ​cells/mm3 in Thailand

Characteristics of suboptimal immune response after initiating antiretroviral therapy among people living with HIV with a pre-treatment CD4 T cell count <200 ​cells/mm3 in Thailand

Complete recovery of the CD4 T cell count is uncommon among chronically HIV-infected individuals with very low pre-treatment CD4 count. We studied the prevalence of chronically immune recovery and its associated factors including immune characteristics chronic HIV-infected Thais. Treatment-naïve par...

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Veröffentlicht in:Journal of Virus Eradication 2020-09, Vol.6 (3), p.100005-100005, Article 100005
Hauptverfasser: Han, Win Min, Ubolyam, Sasiwimol, Apornpong, Tanakorn, Kerr, Stephen J., Hansasuta, Pokrath, Gatechompol, Sivaporn, Maekanantawat, Wirach, Ruxrungtham, Kiat, Phanuphak, Praphan, Ananworanich, Jintanat, Avihingsanon, Anchalee
Format: Artikel
Sprache:eng
Schlagworte:
Antiretroviral treatment
Asian
Immune characteristics
Original research
Suboptimal immune recovery
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Zusammenfassung:Complete recovery of the CD4 T cell count is uncommon among chronically HIV-infected individuals with very low pre-treatment CD4 count. We studied the prevalence of chronically immune recovery and its associated factors including immune characteristics chronic HIV-infected Thais. Treatment-naïve participants (n ​= ​375) from the HIV-NAT 006 cohort with a pre-treatment CD4 T cell count after initiating antiretroviral therapy (ART) and having achieved a suppressed viremia (HIV-RNA level ​
ISSN:2055-6640
2055-6659
DOI:10.1016/j.jve.2020.100005