Nonbacterial thrombotic endocarditis as a paraneoplastic manifestation of newly diagnosed splenic large B cell lymphoma

Transthoracic echocardiography revealed small oscillating vegetations on aortic cusps without aortic regurgitation and small vegetations on mitral leaflets with mild mitral regurgitation. Due to the unexplained moderate-to-severe thrombocytopenia, which was refractory to platelet transfusion, a bone...

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Veröffentlicht in:The Kaohsiung journal of medical sciences 2023-06, Vol.39 (6), p.644-645
Hauptverfasser: Wang, Ching‐Yun, Lee, Hsiang‐Chun, Lin, Ren‐Jie, Tsai, Jih‐Jin
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Sprache:eng
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Zusammenfassung:Transthoracic echocardiography revealed small oscillating vegetations on aortic cusps without aortic regurgitation and small vegetations on mitral leaflets with mild mitral regurgitation. Due to the unexplained moderate-to-severe thrombocytopenia, which was refractory to platelet transfusion, a bone marrow biopsy revealed a normocellular marrow with myelodysplasia of erythroid and megakaryocyte lineage and a smear result of the increased proportion of plasma cells. [...]we report the first case of the treatment-naïve splenic large B cell lymphoma with NBTE as the paraneoplastic manifestation.
ISSN:1607-551X
2410-8650
DOI:10.1002/kjm2.12677