A Hydrogel-Based Ultrasonic Backscattering Wireless Biochemical Sensing

Wireless monitoring of the physio-biochemical information is becoming increasingly important for healthcare. In this work, we present a proof-of-concept hydrogel-based wireless biochemical sensing scheme utilizing ultrasound. The sensing system utilizes silica-nanoparticle embedded hydrogel deposite...

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Veröffentlicht in:Frontiers in bioengineering and biotechnology 2020-11, Vol.8, p.596370-596370
Hauptverfasser: Nam, Juhong, Byun, Eunjeong, Shim, Hyunji, Kim, Esther, Islam, Sayemul, Park, Moonchul, Kim, Albert, Song, Seung Hyun
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Sprache:eng
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Zusammenfassung:Wireless monitoring of the physio-biochemical information is becoming increasingly important for healthcare. In this work, we present a proof-of-concept hydrogel-based wireless biochemical sensing scheme utilizing ultrasound. The sensing system utilizes silica-nanoparticle embedded hydrogel deposited on a thin glass substrate, which presents two prominent interfaces for ultrasonic backscattering (tissue/glass and hydrogel/glass). To overcome the effect of the varying acoustic properties of the intervening biological tissues between the sensor and the external transducer, we implemented a differential mode of ultrasonic back-scattering. Here, we demonstrate a wireless pH measurement with a resolution of 0.2 pH level change and a wireless sensing range around 10 cm in a water tank.
ISSN:2296-4185
2296-4185
DOI:10.3389/fbioe.2020.596370