Marylosides A-G, Norcycloartane Glycosides from Leaves of Cymbidium Great Flower 'Marylaurencin'

Seven novel norcycloartane glycosides, maryloside A-G ( - ), were isolated from the leaves of Great Flower 'Marylaurencin', along with a known norcycloartane glycoside, cymbidoside ( ). These structures were determined on the basis of mainly NMR experiments as well as chemical degradation...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecules (Basel, Switzerland) Switzerland), 2019-07, Vol.24 (13), p.2504
Hauptverfasser:	Yoneyama, Tatsuro, Iseki, Kanako, Noji, Masaaki, Imagawa, Hiroshi, Hashimoto, Toshihiro, Kawano, Sachiko, Baba, Masaki, Kashiwada, Yoshiki, Yahagi, Tadahiro, Matsuzaki, Keiichi, Umeyama, Akemi
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Survival Chemical degradation Chromatography Crystallography Cymbidium Cymbidium Great Flower ‘Marylaurencin’ Flowers - chemistry Flowers - metabolism Glucose Glycosides Glycosides - chemistry Glycosides - isolation & purification Interferon Lipopolysaccharides Magnetic Resonance Spectroscopy maryloside Models, Molecular Molecular Structure Nitric oxide Nitric Oxide - biosynthesis nitric oxide production norcycloartane glycoside Orchidaceae Orchidaceae - chemistry Orchidaceae - metabolism Plant Extracts - chemistry Plant Extracts - isolation & purification Plant Leaves - chemistry Plant Leaves - metabolism γ-Interferon
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Seven novel norcycloartane glycosides, maryloside A-G ( - ), were isolated from the leaves of Great Flower 'Marylaurencin', along with a known norcycloartane glycoside, cymbidoside ( ). These structures were determined on the basis of mainly NMR experiments as well as chemical degradation and X-ray crystallographic analysis. The isolated compounds ( - and ) were evaluated for the inhibitory activity on lipopolysaccharide (LPS) and interferon-γ (IFN-γ)-stimulated nitric oxide (NO) production in RAW 264.7 cells. Consequently, and exhibited moderate activity.
ISSN:	1420-3049 1420-3049
DOI:	10.3390/molecules24132504