High prevalence of hepatitis A in indigenous population in north Brazil

High prevalence of hepatitis A in indigenous population in north Brazil

Little is known about hepatitis A virus (HAV) prevalence in indigenous communities. This study aims to evaluate the prevalence of HAV in indigenous community compared to urban population located at Western Amazon in Brazil. A total of 872 serum samples were obtained from 491 indigenous and 381 non i...

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Veröffentlicht in:BMC research notes 2020-09, Vol.13 (1), p.458-458, Article 458
Hauptverfasser: de Paula, Vanessa Salete, Milagres, Flavio Augusto Pádua, Oliveira, Guilherme de Macêdo, Miguel, Juliana Custódio, Cruz, Helena Medina, Scalioni, Leticia de Paula, Marques, Vanessa Alves, Magalhães, Monica de Avelar Figueiredo Mafra, Romão, Anselmo Rocha, Gracie, Renata, Villar, Livia Melo
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aging
Brazil - epidemiology
Census of Population
Distribution
Gender
Health aspects
Hepatitis A
Hepatitis A - epidemiology
Hepatitis A Antibodies
Humans
Immunization
Immunoglobulin M
Indigenous peoples
Indigenous population
Infections
Informed consent
Laboratories
Male
Management
Population Groups
Prevalence
Prevalence studies (Epidemiology)
Research Note
Ribonucleic acid
RNA
Sanitation
Seroepidemiologic Studies
Spatial distribution
Urban areas
Vaccination
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Zusammenfassung:Little is known about hepatitis A virus (HAV) prevalence in indigenous communities. This study aims to evaluate the prevalence of HAV in indigenous community compared to urban population located at Western Amazon in Brazil. A total of 872 serum samples were obtained from 491 indigenous and 381 non indigenous individuals aging 0 to 90 years. Samples were tested for total and IgM anti-HAV and positive IgM samples were tested for HAV RNA. The overall prevalence of total anti-HAV was 87%, increased according age showing 100% of prevalence in those aging more than 30 years (p 
ISSN:1756-0500
1756-0500
DOI:10.1186/s13104-020-05303-y