STRUCTURE ELUCIDATION OF ALKALOIDS FROM LEAVES OF Voacanga foetida (Bl.) Rolfe OF LOMBOK ISLAND

The leaves of Voacanga foetida (Bl.) Rolfe, have been used ethnomedically for the treatment of wounds, itches, and swellings particularly in Lombok island. A phytochemical study has been done to investigate chemical compounds responsible against the cause of the diseases. By separating alkaloidal fraction from the leaves was found voacristine 1 as the major alkaloidal compound, and voacangine 2 and coronaridine 3 as the minor components. The structure elucidation of the compounds was carried out on the basis of spectroscopy data. A structure revision of voacristine 1 was also reported. Keywords: alkaloids, Voacanga foetida, Lombok