From the Cochrane Library: Topical Tacrolimus for Atopic Dermatitis

Emotional stress from uncontrolled eczema can be displaced on coworkers, students, and teachers, affecting the entire community. [...]effective eczema management potentially has far-reaching benefits. Additionally, patients may experience treatment-resistant eczema. [...]cost-effective alternative treatments with fewer side effects may be prudent. Tacrolimus is a suitable and effective alternative under these conditions. [...]tacrolimus appears to be an effective treatment for eczema.