Case Report: Early detection of lung carcinoid in an asymptomatic individual by blood-test initiated PET-CT imaging

We present the case of a 53-year-old woman who was diagnosed with early-stage lung cancer by targeted cancer screening consisting of an immunological biopsy-based blood test followed by radiological imaging. The PanTum Detect blood test detects the biomarkers Apo10/DNaseX and Transketolase-like 1 (T...

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Veröffentlicht in:Frontiers in oncology 2023-06, Vol.13, p.1177237
Hauptverfasser: Burg, Simon, Smeets, Ralf, Gosau, Martin, Failing, Katja, Grust, Audrey Laure Céline
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Sprache:eng
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Zusammenfassung:We present the case of a 53-year-old woman who was diagnosed with early-stage lung cancer by targeted cancer screening consisting of an immunological biopsy-based blood test followed by radiological imaging. The PanTum Detect blood test detects the biomarkers Apo10/DNaseX and Transketolase-like 1 (TKTL1) in circulating macrophage-like cells from peripheral blood samples to identify asymptomatic individuals with a high risk for malignancy. The elevated blood test values initiated an F-FDG PET/CT visualization for further clarification. In this case, imaging indicated a lung carcinoma in the right upper lobe. A biopsy confirmed the presence of a lung carcinoma, which was removed surgically. Histologic examination revealed a typical I A2 carcinoid, which was completely removed, making further therapy obsolete.
ISSN:2234-943X
2234-943X
DOI:10.3389/fonc.2023.1177237