Naturally occurring non-ABO alloantibodies in voluntary blood donors

Normally, an individual has anti-A and anti-B antibodies present. Pregnancy, transfusion, transplantation, or injections of immunogenic material may cause immunization to red cell antigens. Sometimes, no specific immunizing event can be identified for the production of an antibody against a red cell antigen. Such antibodies are called naturally occurring antibodies.[1],[2]This study was a descriptive study done prospectively; it was carried out at the red cell serology laboratory of the department of immunohematology and blood transfusion over a period of 6 months from June to December 2014. This study was approved by the institutional ethics committee.