Evaluation of Antibacterial and Antifungal Properties of Low Molecular Weight Chitosan Extracted from Hermetia illucens Relative to Crab Chitosan

This study shows the research on the depolymerisation of insect and crab chitosans using novel enzymes. Enzyme preparations containing recombinant chitinase Chi 418 from , chitinase Chi 403, and chitosanase Chi 402 from , all belonging to the family GH18 of glycosyl hydrolases, were used to depolyme...

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Veröffentlicht in:Molecules (Basel, Switzerland) Switzerland), 2022-01, Vol.27 (2), p.577
Hauptverfasser: Khayrova, Adelya, Lopatin, Sergey, Shagdarova, Balzhima, Sinitsyna, Olga, Sinitsyn, Arkady, Varlamov, Valery
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Sprache:eng
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Zusammenfassung:This study shows the research on the depolymerisation of insect and crab chitosans using novel enzymes. Enzyme preparations containing recombinant chitinase Chi 418 from , chitinase Chi 403, and chitosanase Chi 402 from , all belonging to the family GH18 of glycosyl hydrolases, were used to depolymerise a biopolymer, resulting in a range of chitosans with average molecular weights (M ) of 6-21 kDa. The depolymerised chitosans obtained from crustaceans and insects were studied, and their antibacterial and antifungal properties were evaluated. The results proved the significance of the chitosan's origin, showing the potential of as a new source of low molecular weight chitosan with an improved biological activity.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules27020577