Clinical analysis of medication related osteonecrosis of the jaws: A growing severe complication in China

Clinical analysis of medication related osteonecrosis of the jaws: A growing severe complication in China

Medication-related osteonecrosis of the jaws (MRONJ) is an unusual but quite serious complication. However, its mechanism remains unclear, and its treatment protocol is still controversial. Our study involved 201 osteonecrosis of the jaw (ONJ) patients from September 2006 to March 2017. We analyzed...

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Veröffentlicht in:Journal of dental sciences 2018-09, Vol.13 (3), p.190-197
Hauptverfasser: Wang, Qizhang, Liu, Jiyuan, Qi, Shuqun, Liao, Xuejuan, Liu, Dazhong, Pan, Jian
Format: Artikel
Sprache:eng
Schlagworte:
Bisphosphate
Original
Osteonecrosis
Risk factor
Treatment
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Zusammenfassung:Medication-related osteonecrosis of the jaws (MRONJ) is an unusual but quite serious complication. However, its mechanism remains unclear, and its treatment protocol is still controversial. Our study involved 201 osteonecrosis of the jaw (ONJ) patients from September 2006 to March 2017. We analyzed risk factors, clinical characteristics, treatment, etc., by comparing MRONJ with other ONJs. Among 201 patients, MRONJ accounted for 14.71% and it presented a consistent increase tendency. In comparison with other ONJs, we considered advanced age, maxilla lesion, diabetes mellitus, tooth extraction, especially multi-teeth extraction as risk factors (P 
ISSN:1991-7902
2213-8862
DOI:10.1016/j.jds.2017.12.003