ScoreREM: A user-friendly Matlab-GUI for rapid eye movement (REM) sleep microstructure (Phasic/Tonic) annotation and quantification

Rapid eye movement (REM) sleep plays a crucial role in brain functions such as memory consolidation and mood regulation. Alterations in REM sleep and REM sleep behaviour disorders are early biomarkers of neurodegenerative disorders. The microstructure of REM sleep consists of two states: phasic and tonic REM sleep. Quantification of phasic and tonic REM sleep is increasingly pursued. Here we introduce, ScoreREM, an open-source user-friendly MATLAB graphical user interface (GUI) designed for rapid annotation and quantification of Phasic and Tonic REM sleep. Due to its intuitive functionalities and vast array of potential application areas, ScoreREM will serve as an indispensable tool for rapid and accurate REM microstructure quantification in clinical studies.