Lymphoma in Miniature Dachshunds: A retrospective multicenter study of 108 cases (2006‐2018) in Japan

Background Miniature Dachshunds (MD) are predisposed to lymphoma with disease onset of young age and long‐term survival. Objectives To compare clinical features and survival time of lymphoma in MD and non‐MD. Animals One hundred and eight MDs with lymphoma and 149 non‐MD breed dogs with lymphoma were included in the study. Methods This was a retrospective multicenter observational study. Lymphoma was classified based on signalment, histopathology/cytology, and anatomical site of the disease. For each type of lymphoma, median survival time was analyzed by Kaplan‐Meier estimates and life table analysis. Prognostic factors for large‐cell gastrointestinal lymphoma (LGIL) were analyzed using Cox regression. Results Gastrointestinal lymphomas were more common in MDs (53/108) compared to non‐MDs (41/149). The multicentric lymphoma was most common in non‐MD breed dogs (74/149) compared to MDs (33/108). The median age that dog developed lymphoma in MD and non‐MD were both 10 years old; however, lymphomas were more frequently observed in younger dogs (