Life-Threatening Subglottic Stenosis of Granulomatosis with Polyangiitis: A Case Report
Granulomatosis with polyangiitis (GPA) is an autoimmune disease characterized by necrotizing granulomatous inflammation. Subglottic stenosis, which is defined as narrowing of the airway below the vocal cords, has a frequency of 16-23% in GPA. Herein, we present the case of a 39-year-old woman with s...
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Veröffentlicht in: | Medicina (Kaunas, Lithuania) Lithuania), 2021-04, Vol.57 (5), p.423 |
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Sprache: | eng |
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Zusammenfassung: | Granulomatosis with polyangiitis (GPA) is an autoimmune disease characterized by necrotizing granulomatous inflammation. Subglottic stenosis, which is defined as narrowing of the airway below the vocal cords, has a frequency of 16-23% in GPA. Herein, we present the case of a 39-year-old woman with subglottic stenosis manifesting as life-threatening GPA, which was recurrent under systemic immunosuppressive therapy. The patient underwent an emergency tracheostomy, intratracheal intervention, such as carbon dioxide (CO
) laser surgery and intralesional steroid injection via laryngomicroscopic surgery, and laryngotracheal resection with remodeling. Severe subglottic stenosis treatment requires active intratracheal intervention, surgery, and systemic immunosuppressive therapy. |
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ISSN: | 1648-9144 1010-660X 1648-9144 |
DOI: | 10.3390/medicina57050423 |