108 MCY-M11, a CAR-PBMC cell product transiently expressing a mesothelin targeted mRNA CAR, exhibits desirable functional and immune phenotype attributed to sustained antitumor immunity in vitro

108 MCY-M11, a CAR-PBMC cell product transiently expressing a mesothelin targeted mRNA CAR, exhibits desirable functional and immune phenotype attributed to sustained antitumor immunity in vitro

BackgroundMCY-M11, an anti-mesothelin CAR (Meso-CAR) mRNA transfected PBMC cell product manufactured through

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Bibliographische Detailangaben
Veröffentlicht in:Journal for immunotherapy of cancer 2020-11, Vol.8 (Suppl 3), p.A67-A68
Hauptverfasser: Kasimsetty, Sashi, Gatla, Himavanth, Chinnasamy, Dhana
Format: Artikel
Sprache:eng
Schlagworte:
Antigens
Cytotoxicity
Gastric cancer
Genotype & phenotype
Immunity (Disease)
Immunotherapy
Mesothelioma
Ovarian cancer
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Beschreibung
Zusammenfassung:BackgroundMCY-M11, an anti-mesothelin CAR (Meso-CAR) mRNA transfected PBMC cell product manufactured through
ISSN:2051-1426
DOI:10.1136/jitc-2020-SITC2020.0108