The Effect of The Thrombolytic Treatment on Inflammatory Markers in Male Patients with Pulmonary Thromboembolism

Objective: Neutrophil to lymphocyte (NLR) and platelet to lymphocyte (PLR) ratios play an important role in monitoring the progression of the disease and determining the course of the disease in patients with acute pulmonary thromboembolism (APTE). This study aims to determine whether there is any change in NLR, PLR, and C-reactive protein (CRP) in patients with APTE receiving thrombolytic therapy. Materials and Methods: Sixty-five male patients with shortness of breath, chest pain, and palpitations, who were diagnosed with APTE by examinations and thorax computed tomography angiography, and who were hospitalized and given thrombolytic therapy were included in the study. The files of these patients were scanned retrospectively, and NLR and PLR and CRP values were recorded 1-2 days before and 1-4 days after thrombolytic therapy. Then, it was checked whether there was a difference between pre-treatment and post-treatment values. Results: NLR, PLR, CRP and systolic pulmonary artery pressure values decreased statistically significantly in patients with APTE by thrombolytic therapy. Conclusion: NLR, PLR, CRP and sPAP values were found to be statistically significantly decreased with thrombolytic treatment.