Selected Inflammatory and Metabolic Markers in Psoriatic Patients Treated with Goeckerman Therapy

Psoriasis is associated with metabolic activity of adipose tissue which produces pro- and anti-inflammatory adipokines. Goeckerman therapy (GT) represents an effective treatment of psoriasis. This study evaluated variation of selected inflammatory and metabolic markers during GT and the relationship...

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Veröffentlicht in:	Mediators of Inflammation 2015-01, Vol.2015 (2015), p.1158-1165-506
Hauptverfasser:	Fiala, Zdenek, Kremláček, J., Rendarova, Simona, Hamakova, Kvetoslava, Krejsek, Jan, Andrys, Ctirad, Borska, Lenka, Kondelkova, Katerina, Rehacek, Vit
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adiponectin - blood Adult Age Aged Biomarkers Body Mass Index C-Reactive Protein - analysis Cell adhesion & migration Clinical Study Cytokines Diabetes Drug therapy Female Hospitals Humans Inflammation Leptin - blood Male Medicine Metabolic disorders Middle Aged Mortality Obesity Ointments Patient outcomes Polycyclic aromatic hydrocarbons Psoriasis Psoriasis - blood Psoriasis - drug therapy Rodents Severity of Illness Index Sexually transmitted diseases Skin STD Studies
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Zusammenfassung:	Psoriasis is associated with metabolic activity of adipose tissue which produces pro- and anti-inflammatory adipokines. Goeckerman therapy (GT) represents an effective treatment of psoriasis. This study evaluated variation of selected inflammatory and metabolic markers during GT and the relationships between the markers, severity of the disease (PASI score), body mass, and the basic characteristics of the therapy. The study was conducted on a group of patients (n=32) and on a control group (n=24). Before GT, we found significantly elevated levels of proinflammatory CRP (p
ISSN:	0962-9351 1466-1861
DOI:	10.1155/2015/979526