New SARS-CoV-2 Omicron Variant with Spike Protein Mutation Y451H, Kilifi, Kenya, March–May 2023

We report a newly emerged SARS-CoV-2 Omicron subvariant FY.4 that has mutations Y451H in spike and P42L in open reading frame 3a proteins. FY.4 emergence coincided with increased SARS-CoV-2 cases in coastal Kenya during April–May 2023. Continued SARS-CoV-2 genomic surveillance is needed to identify...

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Veröffentlicht in:	Emerging infectious diseases 2023-11, Vol.29 (11), p.2376-2379
Hauptverfasser:	Mwanga, Mike J, Lambisia, Arnold W, Morobe, John Mwita, Murunga, Nickson, Moraa, Edidah, Ndwiga, Leonard, Cheruiyot, Robinson, Musyoki, Jennifer, Mutunga, Martin, GuzmanRincon, Laura M, Sande, Charles, Mwangangi, Joseph, Bejon, Philip, Ochola-Oyier, Lynette Isabella, Nokes, D. James, Agoti, Charles N, Nyiro, Joyce, Githinji, George
Format:	Artikel
Sprache:	eng
Schlagworte:	Causes of Consortia COVID-19 COVID-19 vaccines Disease transmission Epidemics Estimates Genetic aspects Genetic variation Genomes Health aspects Health facilities Influenza Kenya Laboratories Medical research Medicine, Experimental Medicine, Preventive Mutation Omicron Pandemics Preventive health services Proteins Research centers Research Letter respiratory infections SARS SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Testing Vaccines Viruses
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Zusammenfassung:	We report a newly emerged SARS-CoV-2 Omicron subvariant FY.4 that has mutations Y451H in spike and P42L in open reading frame 3a proteins. FY.4 emergence coincided with increased SARS-CoV-2 cases in coastal Kenya during April–May 2023. Continued SARS-CoV-2 genomic surveillance is needed to identify new lineages to inform COVID-19 outbreak prevention.
ISSN:	1080-6040 1080-6059 1080-6059
DOI:	10.3201/eid2911.230894