Multifocality is associated with central neck lymph node metastases in papillary thyroid microcarcinoma

Multifocality is associated with central neck lymph node metastases in papillary thyroid microcarcinoma

This study aimed to assess the predictive factor of multifocality to identify patients at high risk of central lymph node metastasis (CLNM). Papillary thyroid microcarcinoma patients who underwent total or hemi-thyroidectomy with effective unilateral or bilateral central lymph node dissection were e...

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Veröffentlicht in:Cancer management and research 2018-01, Vol.10, p.1527-1533
Hauptverfasser: Zheng, Weihui, Wang, Kejing, Wu, Junzhou, Wang, Wendong, Shang, Jinbiao
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Biopsy
Cancer metastasis
central compartment lymph node
Comparative analysis
Dissection
Goiter
Health aspects
Hospitals
Lymphatic system
Medical prognosis
Medical records
Medical research
metastases
Metastasis
Microscopy
multifocality
Original Research
papillary thyroid microcarcinoma
predictor
Software
Studies
Surgery
Thyroid cancer
Tumors
Ultrasonic imaging
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Beschreibung
Zusammenfassung:This study aimed to assess the predictive factor of multifocality to identify patients at high risk of central lymph node metastasis (CLNM). Papillary thyroid microcarcinoma patients who underwent total or hemi-thyroidectomy with effective unilateral or bilateral central lymph node dissection were enrolled. Multifocality, age, sex, tumor size, extrathyroidal extension, and nodular goiter were significantly associated with CLNM. Multifocality was an independent predictor for CLNM in multivariate analysis. Compared with unifocal disease, the odds ratio for CLNM was 1.447 for patients with ≥2 tumor foci (
ISSN:1179-1322
1179-1322
DOI:10.2147/CMAR.S163263