Great imitator with exclusive oral manifestations

Oral manifestations in syphilis are frequent through the different stages of the disease. Exclusive oral localization in secondary syphilis (SS) is yet uncommon. Delays in diagnosis are frequent in these patients. We describe a case of SS limited to the buccal mucosa with both serological and histological confirmation. Exclusive oral manifestations should prompt diagnosis of syphilis in high‐risk patients as they can represent the only manifestation of the disease.