Cardiac biomarkers in chronic kidney disease are independently associated with myocardial edema and diffuse fibrosis by cardiovascular magnetic resonance

High sensitivity cardiac troponin T (hs-cTnT) and NT-pro-brain natriuretic peptide (NT-pro BNP) are often elevated in chronic kidney disease (CKD) and associated with both cardiovascular remodeling and outcome. Relationship between these biomarkers and quantitative imaging measures of myocardial fib...

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Veröffentlicht in:	Journal of cardiovascular magnetic resonance 2021-06, Vol.23 (1), p.71-71, Article 71
Hauptverfasser:	Arcari, Luca, Engel, Juergen, Freiwald, Tilo, Zhou, Hui, Zainal, Hafisyatul, Gawor, Monika, Buettner, Stefan, Geiger, Helmut, Hauser, Ingeborg, Nagel, Eike, Puntmann, Valentina O
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological markers Biomarkers Brain natriuretic peptide Calcium-binding protein Cardiology Cardiovascular disease Cardiovascular magnetic resonance Chronic kidney disease Chronic kidney failure Comparative analysis Dropsy Edema Epidermal growth factor receptors Fibrosis Gadobutrol Glomerular filtration rate Heart diseases Heart failure Hemodialysis Humans Ischemia Kidney diseases Kidneys Magnetic resonance Magnetic Resonance Spectroscopy Mapping Medical imaging Medical prognosis Medical research Medicine, Experimental Mortality Myocardial ischemia Myocardial remodeling Natriuretic Peptide, Brain Natriuretic peptides Neuroimaging Peptide Fragments Predictive Value of Tests Renal Insufficiency, Chronic - complications Renal Insufficiency, Chronic - diagnosis Resonance Risk factors Serology Troponin Troponin T
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Zusammenfassung:	High sensitivity cardiac troponin T (hs-cTnT) and NT-pro-brain natriuretic peptide (NT-pro BNP) are often elevated in chronic kidney disease (CKD) and associated with both cardiovascular remodeling and outcome. Relationship between these biomarkers and quantitative imaging measures of myocardial fibrosis and edema by T1 and T2 mapping remains unknown. Consecutive patients with established CKD and estimated glomerular filtration rate (eGFR)
ISSN:	1097-6647 1532-429X
DOI:	10.1186/s12968-021-00762-z