Comparing the prevalence of Helicobacter pylori and virulence factors cagA, vacA, and dupA in supra-gingival dental plaques of children with and without dental caries: a case-control study

Helicobacter pylori infection is one of the most common infectious diseases in humans. Dental plaque is considered as a reservoir of this bacterium, which could play an important role in the development of gastrointestinal problems. Our aim was to investigate the prevalence of H. pylori and its viru...

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Veröffentlicht in:	BMC oral health 2022-05, Vol.22 (1), p.170-7, Article 170
Hauptverfasser:	Mehdipour, Aida, Chaboki, Parisa, Rasouli Asl, Farzaneh, Aghaali, Mohammad, Sharifinejad, Negar, Shams, Saeed
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Antigens, Bacterial Bacterial Proteins - genetics Care and treatment Case-Control Studies Child Children Comparative analysis Dental caries Dental Caries - epidemiology Dental decay Dental plaque Dental Plaque - epidemiology Dental Plaque - microbiology Developing countries Development and progression Distribution DMFT Evaluation Female Fluoride treatments Fluorides Gastric cancer Gastrointestinal diseases Genes Genetic aspects Genomes Genotype Health aspects Helicobacter Infections - complications Helicobacter Infections - epidemiology Helicobacter Infections - microbiology Helicobacter pylori Helicobacter pylori - genetics Humans Infections Infectious diseases LDCs Lymphoma Male Oral health Physiological aspects Population Prevalence Statistical analysis Thermal cycling Ulcers Virulence Virulence (Microbiology) Virulence factors Virulence Factors - genetics
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Zusammenfassung:	Helicobacter pylori infection is one of the most common infectious diseases in humans. Dental plaque is considered as a reservoir of this bacterium, which could play an important role in the development of gastrointestinal problems. Our aim was to investigate the prevalence of H. pylori and its virulence factors in dental plaques in children with and without dental caries. Among children aged 6 to 12 years, a total of 72 children were enrolled in the study, including 36 cases with total DMFT/dmft > 3 (case group) and 36 participants with total DMFT/dmft
ISSN:	1472-6831 1472-6831
DOI:	10.1186/s12903-022-02175-5