Drug Repositioning in Glioblastoma: A Pathway Perspective

Drug Repositioning in Glioblastoma: A Pathway Perspective

Glioblastoma multiforme (GBM) is the most malignant primary adult brain tumor. The current standard of care is surgical resection, radiation, and chemotherapy treatment, which extends life in most cases. Unfortunately, tumor recurrence is nearly universal and patients with recurrent glioblastoma typ...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Frontiers in pharmacology 2018-03, Vol.9, p.218-218
Hauptverfasser: Tan, Sze Kiat, Jermakowicz, Anna, Mookhtiar, Adnan K, Nemeroff, Charles B, Schürer, Stephan C, Ayad, Nagi G
Format: Artikel
Sprache:eng
Schlagworte:
blood-brain barrier
drug repurposing
glioblastoma
Library of Integrated Network Based Cell Signatures
LINCS
Pharmacology
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Glioblastoma multiforme (GBM) is the most malignant primary adult brain tumor. The current standard of care is surgical resection, radiation, and chemotherapy treatment, which extends life in most cases. Unfortunately, tumor recurrence is nearly universal and patients with recurrent glioblastoma typically survive
ISSN:1663-9812
1663-9812
DOI:10.3389/fphar.2018.00218