Synthesis and properties of new biotin compounds containing hexyltriethylene glycol chain

The synthesis of a new halogenide containing hexyltriethylene glycol chain functionalized with biotin is reported. The general possibility of this linker to use as the building block for biotinylated compounds syntheses is demonstrated. Two biotinylated esters with different properties for useful su...

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Veröffentlicht in:	Central European journal of chemistry 2012-02, Vol.10 (1), p.113-120
Hauptverfasser:	Matijoška, Algirdas, Charkova, Tatjana, Kuodis, Zenonas, Voiciuk, Vladislava, Eicher-Lorka, Olegas
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biological and Medical Physics Biophysics Biotinylated esters Chemistry Chemistry and Materials Science Chemistry/Food Science Fluorescent probe Geochemistry Research Article Self-assembled monolayers Stilbazolium
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Zusammenfassung:	The synthesis of a new halogenide containing hexyltriethylene glycol chain functionalized with biotin is reported. The general possibility of this linker to use as the building block for biotinylated compounds syntheses is demonstrated. Two biotinylated esters with different properties for useful surface modification and as fluorescence probes for proteins marking were synthesized. The properties of mentioned compounds were investigated by using surface plazmon resonance ellypsometry and fluorescence spectroscopy.
ISSN:	1895-1066 2391-5420 1644-3624 2391-5420
DOI:	10.2478/s11532-011-0113-8