Renal transplantation outcomes in obese patients: a French cohort-based study

Whilst there are a number of publications comparing the relationship between body mass index (BMI) of kidney transplant recipients and graft/patient survival, no study has assessed this for a French patient cohort. In this study, cause-specific Cox models were used to study patient and graft surviva...

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Veröffentlicht in:BMC nephrology 2021-03, Vol.22 (1), p.79-79, Article 79
Hauptverfasser: Foucher, Y, Lorent, M, Albano, L, Roux, S, Pernin, V, Le Quintrec, M, Legendre, C, Buron, F, Morelon, E, Girerd, S, Ladrière, M, Glotz, D, Lefaucher, C, Kerleau, C, Dantal, J, Branchereau, J, Giral, M
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Sprache:eng
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Zusammenfassung:Whilst there are a number of publications comparing the relationship between body mass index (BMI) of kidney transplant recipients and graft/patient survival, no study has assessed this for a French patient cohort. In this study, cause-specific Cox models were used to study patient and graft survival and several other time-to-event measures. Logistic regressions were performed to study surgical complications at 30 days post-transplantation as well as delayed graft function. Among the 4691 included patients, 747 patients were considered obese with a BMI level greater than 30 kg/m . We observed a higher mortality for obese recipients (HR = 1.37, p = 0.0086) and higher risks of serious bacterial infections (HR = 1.24, p = 0.0006) and cardiac complications (HR = 1.45, p 
ISSN:1471-2369
1471-2369
DOI:10.1186/s12882-021-02278-1