Tranexamic acid for reducing blood loss following vaginal delivery: a double-blind randomized controlled trial

Tranexamic acid for reducing blood loss following vaginal delivery: a double-blind randomized controlled trial

Postpartum haemorrhage (PPH) is a major cause of maternal morbidity and mortality worldwide. Tranexamic acid (TXA) is a useful drug for prevention of PPH and merits evaluation in Nigeria, where PPH is the leading cause of maternal death (25%) and severe maternal morbidity. This study evaluates the e...

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Veröffentlicht in:BMC Pregnancy and Childbirth 2022-03, Vol.22 (1), p.178-178, Article 178
Hauptverfasser: Igboke, Francis Nwabueze, Obi, Vitus Okwuchukwu, Dimejesi, Benedict Ikechukwu, Lawani, Lucky Osaheni
Format: Artikel
Sprache:eng
Schlagworte:
Blood loss
Childbirth
Complications and side effects
Dosage and administration
Hemorrhage
Mothers
Patient outcomes
Postpartum haemorrhage
Prevention
Tranexamic acid
Vagina
Vaginal delivery
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Zusammenfassung:Postpartum haemorrhage (PPH) is a major cause of maternal morbidity and mortality worldwide. Tranexamic acid (TXA) is a useful drug for prevention of PPH and merits evaluation in Nigeria, where PPH is the leading cause of maternal death (25%) and severe maternal morbidity. This study evaluates the efficacy of TXA in reducing blood loss following vaginal delivery. This was a double-blind randomized placebo-controlled study on the efficacy and safety of intravenous TXA in reducing blood loss in women undergoing vaginal delivery in a tertiary hospital. Data analysis was conducted with IBM SPSS software (version 20, Chicago II, USA). P-value 
ISSN:1471-2393
1471-2393
DOI:10.1186/s12884-022-04462-z