Novel Approaches in Diagnosing the Role of Inflammation in the Onset Cardiovascular Disorders

There are a number of chemical mediators and pathways involved in the inflammatory onset of cardiovascular disorders. [...]from a therapeutic point of view, it would be most important to focus on the active mediators of inflammation and apoptosis and to manipulate these in order to improve cell function and survival. S. Cui et al. demonstrated that the upregulation of SelS enhances the levels of nitric oxide and endothelial nitric oxide synthase in tumour necrosis factor-α-treated human umbilical vein endothelial cells. [...]the mTOR pathway seems to play an important role in myocardial dysfunction induced by sepsis.