Plasma triglyceride levels and central obesity predict the development of kidney injury in Chinese community older adults

Objective: Despite the achievement of blood glucose, blood pressure targets, the risk for kidney injury remains high among older adults. This observational retrospective study investigated whether high TG or high WC contribute to this high residual risk for kidney injury. Methods: A total of 843 eld...

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Veröffentlicht in:Renal failure 2019-01, Vol.41 (1), p.946-953
Hauptverfasser: Cao, Yujie, Sun, Guangshan, Liu, Rui, Sun, Ao, Zhang, Qian, Li, Yang, Wang, Lele, Chao, Xiangli, Zhou, Xiaojie, Zhang, Sha, Chen, Ruping
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Sprache:eng
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Zusammenfassung:Objective: Despite the achievement of blood glucose, blood pressure targets, the risk for kidney injury remains high among older adults. This observational retrospective study investigated whether high TG or high WC contribute to this high residual risk for kidney injury. Methods: A total of 843 elderly from Dongli Community, Tianjin, China, we selected 666 individuals with a baseline estimated glomerular filtration rate (eGFR) ≥60 mL/min/1.73 m 2 and negative microalbuminuria completing a 3-year follow-up. At baseline, subjects were grouped according to the levels of TG and WC. The primary outcome was the incidence of kidney injury, defined as low eGFR (eGFR 25%) or UACR ≥30 mg/g. Results: Overall, 6.01% developed low eGFR, 11.11% reduced eGFR, 25.98% UACR ≥30 mg/g, and 3.45% low eGFR and UACR ≥30mg/g after 3-year follow-up. TG ≥1.7 mmol/L increased the risk of eGFR
ISSN:0886-022X
1525-6049
1525-6049
DOI:10.1080/0886022X.2019.1655451