Case Report of a Young Adult with Fatal COVID-19 and Abundant SARS-CoV-2 Nucleocapsid Protein and Lipofuscin Accumulation in Tissues

Case Report of a Young Adult with Fatal COVID-19 and Abundant SARS-CoV-2 Nucleocapsid Protein and Lipofuscin Accumulation in Tissues

This is a case report of a young adult who died of COVID-19 twelve days after admission, with coronavirus nucleocapsid protein and lipofuscin found in the heart and kidney tissues, providing further evidence of the role of SARS-CoV-2 in cellular senescence.

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Veröffentlicht in:Heliyon 2024-01, Vol.10 (1), p.e23485, Article e23485
Hauptverfasser: Lira, Rosalia, Luna-Rivero, César, Morales-Bolaños, Francina Valezka, Sandoval-Gutiérrez, José Luis, Moreno-Verduzco, Elsa Romelia, Maldonado-Rodriguez, Angélica, Torres-Flores, Jesús Miguel, Yocupicio-Monroy, Martha, Sevilla-Reyes, Edgar E.
Format: Artikel
Sprache:eng
Schlagworte:
Case Report
case studies
cell senescence
COVID-19
COVID-19 infection
heart
kidneys
lipofuscin
Muscle
Nucleocapsid protein
nucleocapsid proteins
Severe acute respiratory syndrome coronavirus 2
young adults
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Beschreibung
Zusammenfassung:This is a case report of a young adult who died of COVID-19 twelve days after admission, with coronavirus nucleocapsid protein and lipofuscin found in the heart and kidney tissues, providing further evidence of the role of SARS-CoV-2 in cellular senescence.
ISSN:2405-8440
2405-8440
DOI:10.1016/j.heliyon.2023.e23485