Lymph nodal volume in head and neck malignancy: can adding a third dimension improve the detection of nodal metastasis?

Background To compare the diagnostic utility of computed tomography (CT) and ultrasonography (USG) for preoperative determination of metastatic lymph nodes. Methods Head and neck squamous cell carcinoma (HNSCC) cases planned for neck dissection were included. All underwent preoperative neck USG and CT followed by histopathological evaluation after surgery. Sensitivity, specificity, positive and negative predictive value along with accuracy was calculated for each outcome variable. Efficacy was calculated by comparing these to postoperative histopathology. Both imaging modalities were compared with lymph nodal volume. Results Eighty-seven lymph nodes were selected from 30 patients. Median volume on CT was 5412.15 mm 3 for metastatic and 237.7 mm 3 for benign nodes and on ultrasound, 4168.92 mm 3 for metastatic and 233.1 mm 3 for benign nodes ( p