The correlation between diabetes mellitus and COVID-19 severity in Babylon Province

Compared to other pandemic diseases, COVID-19 Coronavirus had the highest transmission rate and high fatality risk. Diabetes is the hand was also one of the most frequent diseases among individuals. This study aimed to evaluate the relationship between diabetic patients infected by COVID-19 and some hematological parameters associated with diabetes and COVID-19. Patients with COVID-19 were diagnosed by PCR and/or chest Computer Topography (CT) scan, eight parameters were detected by AFIAS-6. The results of eight parameters for patients with diabetes mellitus infected with COVID-19 and patients with COVID-19 only showed that the Mean of Fasting Blood Glucose (FBG), Glycated Haemoglobin HbA1c, Insulin Sensitivity (INS) and ferritin show significant differences at (0.000, 0.000, 0.017, 0.000) respectively for the two groups, while Insulin Resistance (INR), Insulin (IN), C-Reactive Protein (CRP) and D-dimer don't show any significant differences for two groups, the statistical analysis performed at P-value ≤ 0.01 and 0.05. Infection duration results showed that the mean Insulin level (IN) and D-dimer show significant differences at (0.033 and 0.011) respectively for all infection duration categories, while FBG, HbA1c, INR, INS, CRP, and ferritin don't show any significant differences for all day's category. The Correlation Coefficients Between diabetes mellitus patients infected with COVID-19 and blood parameters highly correlated between FBG with INR at (0.647), HbA1c with IN at (0.078), INR with IN at (0.791), INS with CT-Scan at (0.058), CRP with D-dimer at (0.287), D-dimer with ferritin at (0.331), Ferritin with infection duration at (0.098). In conclusion, we find that the diabetes mellitus patients infected with COVID-19 suffer from a high increase of inflammatory proteins and parameters associated with diabetes compared to other patients infected with COVID-19 only, making them more susceptible to disease and more deaths compared to other people. [ J Adv Biotechnol Exp Ther 2022; 5(3.000): 445-455]