MicroRNA-128 inhibits the development of human colon cancer by targeting Rho family GTPase 3

MicroRNA-128 inhibits the development of human colon cancer by targeting Rho family GTPase 3

MicroRNA-128 (miRNA-128) exhibits tumour regulatory role in several human cancers including the colon cancer. However, regulatory mechanics of miRNA-128 through Rho family GTPase-3 (RND3) targeting is elusive in colon cancer and was the objective of present study. The results showed that miRNA-128 h...

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Veröffentlicht in:Journal of Taibah University for Science 2022-12, Vol.16 (1), p.139-146
Hauptverfasser: Chang, Yunli, Zhang, Qisheng, Dong, Zhiqi, Gao, Peng, Hai, Yanan
Format: Artikel
Sprache:eng
Schlagworte:
apoptosis
Colon cancer
miRNA-128
Rho GTPase
tumourigenesis
xenograft mice
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Zusammenfassung:MicroRNA-128 (miRNA-128) exhibits tumour regulatory role in several human cancers including the colon cancer. However, regulatory mechanics of miRNA-128 through Rho family GTPase-3 (RND3) targeting is elusive in colon cancer and was the objective of present study. The results showed that miRNA-128 has significant (P 
ISSN:1658-3655
1658-3655
DOI:10.1080/16583655.2022.2027692