Design of Zoom Optical System from Visible to NIR-II for Vivo Fluorescence Imaging Device

Macro vivo fluorescence imaging is becoming more and more important in the medical field. It is also necessary to design the optical design system for the visible light of the NIR-II detector. This paper discusses the design method of the wide spectrum achromatic optical system from visible light to NIR-II. Based on ZEMAX, a wide spectrum zoom system is designed to freely observe experimental targets in the fields of view of 3.1–18.6°. The four components layout was adopted by the wide spectrum zoom system, which is suitable for 8.2 mm (1/2 inch) CCD, with an f-number of 5.0~6.0, zoom range of 25 mm~150 mm, working spectral band of 400 nm~1700 nm, full field MTF ≥ 0.3 at the spatial frequency of 100 lp/mm, and the maximum distortion of ≤±3%. All optical elements adopt the standard spherical, which can correct all kinds of aberrations well and meet each part’s basic processing requirements.