Mid-term outcomes of off-pump versus on-pump coronary artery bypass graft surgery; statistical challenges in comparison

Despite several studies comparing off- and on-pump coronary artery bypass grafting (CABG), the effectiveness and outcomes of off-pump CABG still remain uncertain. In this registry-based study, we assessed 8163 patients who underwent isolated CABG between 2014 and 2016. Propensity score matching (PSM...

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Veröffentlicht in:	BMC cardiovascular disorders 2021-08, Vol.21 (1), p.412-8, Article 412
Hauptverfasser:	Sheikhy, Ali, Fallahzadeh, Aida, Sadeghian, Saeed, Forouzannia, Khalil, Bagheri, Jamshid, Salehi-Omran, Abbas, Tajdini, Masih, Jalali, Arash, Pashang, Mina, Hosseini, Kaveh
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Blood pressure Cardiopulmonary Bypass - adverse effects Cardiopulmonary Bypass - mortality Cardiopulmonary Bypass - statistics & numerical data Cardiovascular disease Cholesterol Comparative analysis Comparative Effectiveness Research Coronary artery Coronary artery bypass Coronary Artery Bypass - adverse effects Coronary Artery Bypass - mortality Coronary Artery Bypass - statistics & numerical data Coronary artery bypass grafting Coronary Artery Bypass, Off-Pump - adverse effects Coronary Artery Bypass, Off-Pump - mortality Coronary Artery Bypass, Off-Pump - statistics & numerical data Coronary Artery Disease - diagnosis Coronary Artery Disease - mortality Coronary Artery Disease - surgery Coronary vessels Diabetes Family medical history Female Heart Heart surgery Hemoglobin Humans Hypertension Intubation Male Medical imaging Methods Middle Aged Models, Statistical Mortality Off-pump Patient outcomes Patients Propensity Score Prospective Studies Registries Risk Assessment Risk Factors Statistical analysis Surgeons Surgery Surgical revascularization Time Factors Treatment Outcome Variables
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Beschreibung
Zusammenfassung:	Despite several studies comparing off- and on-pump coronary artery bypass grafting (CABG), the effectiveness and outcomes of off-pump CABG still remain uncertain. In this registry-based study, we assessed 8163 patients who underwent isolated CABG between 2014 and 2016. Propensity score matching (PSM), inverse probability of weighting (IPW) and covariate adjustment were performed to correct for and minimize selection bias. The overall mean age of the patients was 62 years, and 25.7% were women. Patients who underwent off-pump CABG had shorter length of hospitalization (p
ISSN:	1471-2261 1471-2261
DOI:	10.1186/s12872-021-02213-0