Association between Organochlorine Pesticides and Vitamin D in Female Subjects

In human population studies, organochlorine pesticides (OCPs) have been linked to vitamin D deficiency. Therefore, this study examined the association between OCPs, vitamin D (cholecalciferol, 25(OH)D ), and the active metabolite 1,25-dihydrovitamin D (1,25(OH) D ) in a cohort of non-obese women. The serum samples of 58 female participants (age-31.9 ± 4.6 years; body mass index (BMI)-25.7 ± 3.7 kg/m ) were screened for 10 indicator OCPs. 25(OH)D and 1,25(OH) D levels were determined via isotope dilution liquid chromatography tandem mass spectrometry. In this cohort, the 25(OH)D and 1,25(OH) D levels were 22.9 ± 11.2 ng/mL and 0.05 ± 0.02 ng/mL, respectively, with 28 participants classified as 25(OH)D -deficient (