Content of cobalt in biological medias of full-term newborns as predictor of perinatal hypoxic damage of central nervous system

The aim of the study: to determine cobalt content in biological media of newborns with hypoxic-ischemic lesions of central nervous system (CNS ) and to study its properties as predictor in formation of hypoxia outcomes, to investigate cobalt ensuring the in mother-placenta-fetus system. Materials and methods. Co content was determined in serum and erythrocytes of 30 pregnant women and their 30 newborns with hypoxic-ischemic damage of CNS. The content of trace elements in biomaterials of newborns and their mothers was determined by atomic absorption spectrophotometry on a spectrophotometer C-115M1, manufacturing NGO "Selmi" (Ukraine). We used methods of variation statistics suitable for biomedical research and method Wald-Genkin to determine the properties as prediktor of cobalt. Results. For women which born babies with hypoxia was typical significant serum-erythrocytic imbalance ofCo.In case of hypoxia we determined decreasing of barrier function (96.2%) and depositing function of Co (79.3%), indicating a dysfunction of placenta in case of hypoxia. Content of Co in serum of newborns with hypoxic damage of CNS Co was significantly (p